ACTIVATION OF THE BASAL GANGLIA DURING VOCAL COMMUNICATION IN A NON-HUMAN PRIMATE

Anna Gabriely Barroso de Sá; Cristiano Soares Simões; Sidarta Ribeiro; Daniel Yasumasa Takahashi

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Trabalho

Título do Trabalho

ACTIVATION OF THE BASAL GANGLIA DURING VOCAL COMMUNICATION IN A NON-HUMAN PRIMATE

Autores

Anna Gabriely Barroso de Sá
Cristiano Soares Simões
Sidarta Ribeiro
Daniel Yasumasa Takahashi

Modalidade

Resumo simples

Área temática

Estudos do comportamento

Data de Publicação

29/12/2023

País da Publicação

Brasil

Idioma da Publicação

Português

Página do Trabalho

https://www.even3.com.br/anais/simpsicobioufrn/749005-activation-of-the-basal-ganglia-during-vocal-communication-in-a-non-human-primate

ISBN

978-65-272-0168-7

Palavras-Chave

marmoset; vocalization; egr-1; basal ganglia.

Resumo

Flexible speech is one of the core aspects of human communication. Despite being considered uniquely human among primates, recent evidence shows that some non-human primates also have vocal plasticity. Marmosets (Callithrix jacchus), a New World monkey, exhibit exceptionally flexible vocalizations. Given the homologies between human and marmoset brains, investigating the neural correlates of vocal flexibility in marmosets leads to a deeper understanding of the origin of vocal flexibility in humans. Much of the literature on the neural basis of primate vocalization focuses on cortical areas, leaving fundamental gaps in our knowledge about the role of subcortical regions. Basal ganglia are related to the choice/initiation of actions, fine motor control, and learning of motor sequences; hence, it is likely to be relevant for vocal flexibility. Here, using histological data previously collected, we test the hypothesis that basal ganglia in marmosets activate during vocal communication. We use the expression of immediate-early gene egr-1 to map neural activation in basal ganglia in three marmoset groups (n = 2 per group). The first group did not vocalize/heard vocalizations during testing (C), the second heard playback vocalizations but did not vocalize (H/O), and the third heard playback calls and vocalized (H/V). Using stereological methods, we quantified the number of cells expressing erg-1 in the caudate nucleus (Cd) and putamen (Pu). Our results show an increase in egr-1 expression in both areas in the H/O condition (Cd: µ±ep, 193.33±13.87cells/mm2; Pu: 167.5±14.67cells/mm2) compared to the C condition (Cd: 110.52±11.33cells/mm2; Pu: 77.5±9.35cells/mm2; p<0.001, t-test). We also observed a significant increase in egr-1 expression in the same areas in the H/V condition (Cd: 502.10±24.55cells/mm2; Pu: 715.55±34.85cells/mm2) compared to the H/O condition (p<0.001, t-test). These results indicate that basal ganglia activate during listening and vocal production, supporting our hypothesis.

Título do Evento: X Conferência & XV Simpósio de Psicobiologia
Cidade do Evento: Natal
Título dos Anais do Evento: Anais do Simpósio de Psicobiologia: Psicobiotecnologia - interface entre inovação e comportamento
Nome da Editora: Even3
Meio de Divulgação: Meio Digital

Como citar

SÁ, Anna Gabriely Barroso de et al.. ACTIVATION OF THE BASAL GANGLIA DURING VOCAL COMMUNICATION IN A NON-HUMAN PRIMATE.. In: Anais do Simpósio de Psicobiologia: Psicobiotecnologia - interface entre inovação e comportamento. Anais...Natal(RN) Centro de Biociências, 2023. Disponível em: https//www.even3.com.br/anais/simpsicobioufrn/749005-ACTIVATION-OF-THE-BASAL-GANGLIA-DURING-VOCAL-COMMUNICATION-IN-A-NON-HUMAN-PRIMATE. Acesso em: 26/12/2024